Cited, evidence-based answers
Every response is grounded in 21 CFR sections and FDA guidance, with inline citations you can verify and follow to the source.
FDA Regulatory Intelligence
Navigate FDA regulations with confidence.
CFR21 is an AI research assistant that answers your questions about 21 CFR and FDA guidance — with citations, evidence, and interactive visualizations from a knowledge graph of 80,000+ regulatory sources.
14-day free trial · No credit card to explore · Cancel anytime
80,000+
Regulatory nodes
21 CFR
Full title coverage
2,200+
FDA guidance docs
Capabilities
Regulatory research, grounded in evidence.
Not a generic chatbot. CFR21 is purpose-built for FDA regulatory work, with answers you can verify down to the section.
Interactive knowledge graph
See how regulations, guidance, and product categories connect. Explore cross-references in a force-directed visualization.
Hybrid semantic search
BM25 keyword matching fused with vector similarity surfaces the most relevant passages — not just keyword hits.
Always current
An automated ingestion pipeline tracks new and updated FDA guidance and eCFR regulations as they are published.
Rich visual outputs
Approval roadmaps, submission checklists, comparison tables, and timelines — generated from your questions.
Built for professionals
Designed for regulatory affairs, quality, and consulting teams who need answers they can stand behind.
How it works
From question to cited answer in seconds.
01
Ask in plain English
Pose any question about FDA regulations, submission pathways, or compliance requirements.
02
We query the graph
CFR21 searches a knowledge graph of 80,000+ regulatory nodes using hybrid semantic retrieval.
03
Get a cited answer
Receive an evidence-based response with citations and interactive visualizations you can trust.
Knowledge graph
See the connections others miss.
Regulations don't exist in isolation. CFR21 maps cross-references, authorizing statutes, product categories, and semantic topics — so you understand not just the rule, but everything it touches.
Explore the graphStart your 14-day free trial.
Join regulatory professionals using CFR21 to research faster and cite with confidence.